Complement regulator-acquiring surface protein

From Proteopedia

CRASP-2 (PDB code 4cbe) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Complement regulator-acquiring surface protein (CRASP) are proteins of the Lyme-disease causing bacteria Borrelia burgdorferi which bind to several human extracellular matrix proteins. For details on CRASP-1 see Borrelia burgdorferi Complement Regulator-Acquiring Surface Protein 1.[1][2] Disease Lyme-disease adhesion factors.

3D structures of Complement regulator-acquiring surface protein

Updated on 19-October-2017

References

1. ↑ Hallstrom T, Haupt K, Kraiczy P, Hortschansky P, Wallich R, Skerka C, Zipfel PF. Complement regulator-acquiring surface protein 1 of Borrelia burgdorferi binds to human bone morphogenic protein 2, several extracellular matrix proteins, and plasminogen. J Infect Dis. 2010 Aug 15;202(3):490-8. doi: 10.1086/653825. PMID:20565259 doi:10.1086/653825
2. ↑ Brangulis K, Petrovskis I, Kazaks A, Bogans J, Otikovs M, Jaudzems K, Ranka R, Tars K. Structural characterization of CspZ, a complement regulator factor H and FHL-1 binding protein from Borrelia burgdorferi. FEBS J. 2014 Apr 7. doi: 10.1111/febs.12808. PMID:24702793 doi:http://dx.doi.org/10.1111/febs.12808