Interleukin-15/Sandbox
From Proteopedia
(General Description) Interleukin-15 (IL-15) is a 14-15kDa cytokine with similar biological functions to IL-2 (Kirman, 1998), eliciting such responses as differentiation and proliferation of lymphocytes, expression of cytolytic programs in lymphocytic killer cells, and chemoattraction of T cells (Chae, 1996). IL-15 has also been implicated in homeostatic proliferaton and deemed necessary for CD8+ T cell memory. In high enough concentrations, IL-15 has been implicated in chronic inflammatory diseases.
Structure & Function
Structure
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| Mouse interleukin-15 complex with interleukin-15 receptor α chain and benzamidine, 2psm | |||||||||
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| Gene: | Il15 (Mus musculus), Il15ra (Mus musculus) | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB, TOPSAN | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
3D structures of interleukin
