Function
Ketol-acid reductoisomerase (KARI) is a bifunctional enzyme which catalizes two steps in the biosynthesis of branched-chain amino acids. KARI catalyzes the isomerization of alkyls and the NADPH-dependent reduction of a 2-ketoacid[1]. There are two forms of KARI. A short form – Class I – found in fungi and most bacteria and a long form. For the active site see Arnold lab: coenzyme specificity – Class II – found in plants.
3D Structures of Ketol-acid reductoisomerase
Ketol-acid reductoisomerase 3D structures
