Molecular Playground/Taxol

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Paclitaxel (also known as Taxol)

References

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  2. Wilson SA, Roberts SC. Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules. Plant Biotechnol J. 2012 Apr;10(3):249-68. doi: 10.1111/j.1467-7652.2011.00664.x., Epub 2011 Nov 8. PMID:22059985 doi:http://dx.doi.org/10.1111/j.1467-7652.2011.00664.x
  3. Carvacho HB, Perez C, Zuniga G, Mahn A. Effect of methyl jasmonate, sodium selenate and chitosan as exogenous elicitors on the phenolic compounds profile of broccoli sprouts. J Sci Food Agric. 2014 Sep;94(12):2555-61. doi: 10.1002/jsfa.6596. Epub 2014 Mar , 18. PMID:24497113 doi:http://dx.doi.org/10.1002/jsfa.6596
  4. Gu XC, Chen JF, Xiao Y, Di P, Xuan HJ, Zhou X, Zhang L, Chen WS. Overexpression of allene oxide cyclase promoted tanshinone/phenolic acid production in Salvia miltiorrhiza. Plant Cell Rep. 2012 Dec;31(12):2247-59. doi: 10.1007/s00299-012-1334-9. Epub, 2012 Aug 29. PMID:22926031 doi:http://dx.doi.org/10.1007/s00299-012-1334-9
  5. Sabater-Jara AB, Onrubia M, Moyano E, Bonfill M, Palazon J, Pedreno MA, Cusido RM. Synergistic effect of cyclodextrins and methyl jasmonate on taxane production in Taxus x media cell cultures. Plant Biotechnol J. 2014 Oct;12(8):1075-84. doi: 10.1111/pbi.12214. Epub 2014 Jun, 9. PMID:24909837 doi:http://dx.doi.org/10.1111/pbi.12214
  6. Sasaki Y, Asamizu E, Shibata D, Nakamura Y, Kaneko T, Awai K, Amagai M, Kuwata C, Tsugane T, Masuda T, Shimada H, Takamiya K, Ohta H, Tabata S. Monitoring of methyl jasmonate-responsive genes in Arabidopsis by cDNA macroarray: self-activation of jasmonic acid biosynthesis and crosstalk with other phytohormone signaling pathways. DNA Res. 2001 Aug 31;8(4):153-61. PMID:11572481

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Sarah Wilson, Alexander Berchansky, Rohan Patil, Elizabeth Cummings, Michal Harel, Lynmarie K Thompson

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