SARS-CoV-2 protein ORF7a

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Accessory Protein 7a from SARS-CoV2 (PDB entry 6w37)

References

  1. Michel, Christian Jean; Mayer, Claudine; Poch, Olivier; Thompson, Julie Dawn (2020): Characterization of accessory genes in coronavirus genomes. In: Virol J 17 (1), S. 131. DOI: 10.1186/s12985-020-01402-1
  2. Fielding, Burtram C.; Tan, Yee-Joo; Shuo, Shen; Tan, Timothy H. P.; Ooi, Eng-Eong; Lim, Seng Gee et al. (2004): Characterization of a unique group-specific protein (U122) of the severe acute respiratory syndrome coronavirus. In: Journal of Virology 78 (14), S. 7311–7318. DOI: 10.1128/JVI.78.14.7311-7318.2004.
  3. Hänel, Karen; Stangler, Thomas; Stoldt, Matthias; Willbold, Dieter (2006): Solution structure of the X4 protein coded by the SARS related coronavirus reveals an immunoglobulin like fold and suggests a binding activity to integrin I domains. In: Journal of biomedical science 13 (3), S. 281–293. DOI: 10.1007/s11373-005-9043-9
  4. Vasilenko, Natalia; Moshynskyy, Igor; Zakhartchouk, Alexander (2010): SARS coronavirus protein 7a interacts with human Ap4A-hydrolase. In: Virol J 7, S. 31. DOI: 10.1186/1743-422X-7-31.
  5. Francis K. Yoshimoto (2020): The Proteins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2 or n-COV19), the Cause of COVID-19. In: Protein J 39 (3), S. 198–216. DOI: 10.1007/s10930-020-09901-4.
  6. Tan, Yee-Joo; Fielding, Burtram C.; Goh, Phuay-Yee; Shen, Shuo; Tan, Timothy H. P.; Lim, Seng Gee; Hong, Wanjin (2004): Overexpression of 7a, a protein specifically encoded by the severe acute respiratory syndrome coronavirus, induces apoptosis via a caspase-dependent pathway. In: Journal of Virology 78 (24), S. 14043–14047. DOI: 10.1128/JVI.78.24.14043-14047.2004.
  7. Tan, Ying-Xim; Tan, Timothy H. P.; Lee, Marvin J-R; Tham, Puay-Yoke; Gunalan, Vithiagaran; Druce, Julian et al. (2007): Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL protein. In: Journal of Virology 81 (12), S. 6346–6355. DOI: 10.1128/JVI.00090-07.
  8. Vasilenko, Natalia; Moshynskyy, Igor; Zakhartchouk, Alexander (2010): SARS coronavirus protein 7a interacts with human Ap4A-hydrolase. In: Virol J 7, S. 31. DOI: 10.1186/1743-422X-7-31.
  9. Yuan, Xiaoling; Wu, Jie; Shan, Yajun; Yao, Zhenyu; Dong, Bo; Chen, Bo et al. (2006): SARS coronavirus 7a protein blocks cell cycle progression at G0/G1 phase via the cyclin D3/pRb pathway. In: Virology 346 (1), S. 74–85. DOI: 10.1016/j.virol.2005.10.015.

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