Sandbox1257
From Proteopedia
This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!
DNA:RNA interactions
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| 124d, 1 NMR models () | |||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
The shown representation is a DNA:RAN hybrid duplex. This is the
in orange and this is the in green. Notice that all hydrogen bonds between the bases are . We can choose to see the base pairs, which show very neatly. First, the G-C pairs: are in blue and are in yellow. Similarly, we can see the in red and the in purple (note that the RNA has U nucleotides instead of T). Furthermore, we can also see the bonding with each other (never with themselves) for a more general view of the bases. In this generic RNA:DNA hybrid all hydrogen bonds between the bases are through the , as shown for the dG-C pair. If we choose to see the in the hybrid, as we'd expect, the whole complex shines: the backbone and the nucleotides are negatively charged.
