Serine palmitoyltransferase 3D structures

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3D structures of serine palmitoyltransferase

Updated on 16-November-2023

7k0l – hSPT1 + SPT2 + SPT small subunit A + antibiotic + PLP – human – Cryo EM
7k0k – hSPT1 + SPT2 + SPT small subunit A + sphinganine derivative – Cryo EM
7k0i, 7k0j – hSPT1 + SPT2 + SPT small subunit A – Cryo EM
7k0q – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + antibiotic + PLP – Cryo EM
6m4n, 6m4o, 7k0m, 7k0n, 7k0o, 7k0p, 7yj1 – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + PLP – Cryo EM
7yj2 – hSPT1 + SPT2 (mutant) + SPT small subunit A + ORM1-like protein + PLP – Cryo EM
7yiy, 7yiu – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + PLP + C6-ceramide – Cryo EM
7cqi, 7cqk – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + PLP derivative + substrate – Cryo EM
8c80, 8c82 – ySPT1 + SPT2 + SPT small subunit A + ORM1 + TSC3 + PLP + substrate – yeast - Cryo EM
8c81 – ySPT1 + SPT2 + SPT small subunit A + ORM1 + TSC3 + SAC1 + PLP-Gly - Cryo EM
2jg2 – PpSPT + aldimine – Pseudomonas paucimobilis
2jgt – PpSPT
2w8j - SpSPT + aldimine – Sphingomonas paucimobilis
2w8t, 2w8u, 2w8v, 2w8w - SpSPT (mutant) + aldimine
4bmk - SpSPT (mutant) + antibiotic + PLP
2xbn – SpSPT + PLP derivative
8guh - SmSPT – Sphingobacterium multivorum
8h1w - SmSPT + PLP
8h20 - SmSPT + PLP-Gly
8h29 - SmSPT + PLP-Thr
8h21 - SmSPT + PLP-Ala
8h1q - SmSPT + PLP-Ser
8h1y - SmSPT + PLP-homoSer
3a2b – SmSPT + PLP + serine
2x8u - SwSPT + PLP derivative – Sphingomonas wittichii
7e13 - SPT + PLP – Erigeron canadensis

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Michal Harel

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