Thiol peroxidase (TPX) is part of an oxidative stress defense system that uses thioredoxin and thioredoxin reductase to reduce alkyl hydroperoxides. TPX is an antioxidant which reduces peroxides and inhibits hydrogen peroxide response. TPX is also implicated in activation of transcription factors and signaling[1]. See also Bacterioferritin comigratory protein.
For yeast thiol peroxidase see Peroxiredoxin
3D structures of thiol peroxidase
Thiol peroxidase 3D structures
References
- ↑ Flohe L, Toppo S, Cozza G, Ursini F. A comparison of thiol peroxidase mechanisms. Antioxid Redox Signal. 2011 Aug 1;15(3):763-80. doi: 10.1089/ars.2010.3397. Epub , 2010 Nov 1. PMID:20649470 doi:http://dx.doi.org/10.1089/ars.2010.3397
