Uncoupling Protein 2

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Uncoupling Protein 2 (UCP2) in Diabetes

NMR structure of mouse uncoupling protein 2 (PDB code 2lck)

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References

  1. Mitochondrial Disorder Medical Information. http://www.mitoaction.org/medical-information.
  2. Luft, R.; Luthman, H. Physiopathology of mitochondria. From Luft's disease to aging and diabetes. https://www.ncbi.nlm.nih.gov/pubmed/8366714.
  3. Sreedhar, A.; Zhao, Y. Uncoupling protein 2 and metabolic diseases. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477468/
  4. Maassen, J. A.; Leen; Hart; Essen, E. van; Heine, R. J.; Nijpels, G.; Tafrechi, R. S. J.; Raap, A. K.; Janssen, G. M. C.; Lemkes, H. H. P. J. Mitochondrial Diabetes. http://diabetes.diabetesjournals.org/content/53/suppl_1/S103.
  5. Sivitz, W. I.; Yorek, M. A. Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824521/.
  6. Chan, C. B.; Saleh, M. C.; Koshkin, V.; Wheeler, M. B. Uncoupling Protein 2 and Islet Function. http://diabetes.diabetesjournals.org/content/53/suppl_1/S136.
  7. Sophie Rousset, M.-C. A.-G.; Mozo, J.; Bruno Miroux, A.-M. C.-D.; Bouillaud, F.; Ricquier, D. The Biology of Mitochondrial Uncoupling Proteins. http://diabetes.diabetesjournals.org/content/53/suppl_1/S130.

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