From Proteopedia

Homo sapiens Insulin Receptor Ectodomain

Human Insulin Receptor and 6SOF Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol [1] to the rescue. Contents 1 Introduction 2 Function 2.1 Conformation Change 3 Disease 4 Relevance 5 Structural highlights Introduction Function Conformation Change Figure 1. The coolest image of this protein!!! Disease Type 2 Diabetes Relevance Structural highlights This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

References

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1. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
2. ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
3. ↑ Wilcox G. Insulin and insulin resistance. Clin Biochem Rev. 2005 May;26(2):19-39. PMID:16278749

Student contributors

• Alyssa Ritter
• Harrison Smith