10eh
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De novo assembled CBF3-CEN complex
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Structural highlights
FunctionCBF3A_YEAST Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters. Contents | ||||||||||||||||||||
This page was last modified 12:35, 1 July 2026.