10jc
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CCAN dimer purified from budding yeast
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Structural highlights
FunctionCENPH_YEAST Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.[1] References | ||||||||||||||||||
This page was last modified 07:14, 8 July 2026.