13eu

Cryo-EM structure of HAdV-C6 hexon trimer in complex with human coagulation factor X (FX)

spinqualitylabelsall models 13eu, resolution 3.26Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 13eu is a 4 chain structure with sequence from Homo sapiens and Human adenovirus 6. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.26Å Ligands: CA, CGU Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function B2ZWX4_ADE06 Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus.[ARBA:ARBA00024662][HAMAP-Rule:MF_04051]

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