1a59

COLD-ACTIVE CITRATE SYNTHASE

spinqualitylabelsall models 1a59, resolution 2.09Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1a59 is a 1 chain structure with sequence from Antarctic bacterium DS2-3R. The September 2007 RCSB PDB Molecule of the Month feature on Citrate Synthase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2007_9. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.09Å Ligands: CIT, COA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PRPC_ABDS2 Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Citrate Synthase 3D structures

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