Structural highlights 1c1d is a 2 chain structure with sequence from Rhodococcus sp. . Full crystallographic information is available from OCA . For a guided tour on the structure components use FirstGlance . Method: X-ray diffraction, Resolution 1.25Å Ligands: IPA , K , NA , NAI , PHE , PO4 Resources: FirstGlance , OCA , PDBe , RCSB , PDBsum , ProSAT
Function DHPH_RHOSO Catalyzes the reversible NAD(+)-dependent oxidative deamination of L-phenylalanine to phenylpyruvate.[ 1] [ 2]
Evolutionary Conservation CheckConSurfDB . You may read the explanation of the method and the full data available from ConSurf .
References
↑ Brunhuber NM, Thoden JB, Blanchard JS, Vanhooke JL. Rhodococcus L-phenylalanine dehydrogenase: kinetics, mechanism, and structural basis for catalytic specificity. Biochemistry. 2000 Aug 8;39(31):9174-87. PMID:10924111
↑ Brunhuber NM, Banerjee A, Jacobs WR Jr, Blanchard JS. Cloning, sequencing, and expression of Rhodococcus L-phenylalanine dehydrogenase. Sequence comparisons to amino-acid dehydrogenases. J Biol Chem. 1994 Jun 10;269(23):16203-11 PMID:8206922
