1gx7

Best model of the electron transfer complex between cytochrome c3 and [Fe]-hydrogenase

spinqualitylabelsall models 1gx7 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1gx7 is a 3 chain structure with sequence from Desulfovibrio vulgaris str. Hildenborough. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Hybrid , Solution NMR , Theoretical Model, 1 model Ligands: CMO, CYN, FE2, HEC, PDT Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PHFL_NITV2 May be involved in hydrogen uptake for the reduction of sulfate to hydrogen sulfide in an electron transport chain. Cytochrome c3 is likely to be the physiological electron carrier for the enzyme. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed Cytochrome c(3) (M(r) 13000) is a low redox potential cytochrome specific of the anaerobic metabolism in sulfate-reducing bacteria. This tetrahemic cytochrome is an intermediate between the [Fe]-hydrogenase and the cytochrome Hmc in Desulfovibrio vulgaris Hildenborough strain. The present work describes the structural model of the cytochrome c(3)-[Fe]-hydrogenase complex obtained by nuclear magnetic resonance restrained docking. This model connects the distal cluster of the [Fe]-hydrogenase to heme 4 of the cytochrome, the same heme found in the interaction with cytochrome Hmc. This result gives evidence that cytochrome c(3) is an electron shuttle between the periplasmic hydrogenase and the Hmc membrane-bound complex. The cytochrome c3-[Fe]-hydrogenase electron-transfer complex: structural model by NMR restrained docking.,ElAntak L, Morelli X, Bornet O, Hatchikian C, Czjzek M, Dolla A, Guerlesquin F FEBS Lett. 2003 Jul 31;548(1-3):1-4. PMID:12885397 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Cytochrome C 3D structures

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