1joc

EEA1 homodimer of C-terminal FYVE domain bound to inositol 1,3-diphosphate

spinqualitylabelsall models 1joc, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1joc is a 2 chain structure with sequence from Homo sapiens. The March 2007 RCSB PDB Molecule of the Month feature on Zinc Fingers by David S. Goodsell is 10.2210/rcsb_pdb/mom_2007_3. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.2Å Ligands: ITP, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function EEA1_HUMAN Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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