1nmo

Structural genomics, protein ybgI, unknown function

spinqualitylabelsall models 1nmo, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1nmo is a 6 chain structure with sequence from Escherichia coli and Escherichia coli O157:H7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.2Å Ligands: FE, MSE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GCH1L_ECOLI Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed BACKGROUND: The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function. RESULTS: The structure of the ybgI protein is a toroid composed of six polypeptide chains forming a trimer of dimers. Each polypeptide chain binds two metal ions on the inside of the toroid. CONCLUSION: The toroidal structure is comparable to that of some proteins that are involved in DNA metabolism. The di-nuclear metal site could imply that the specific function of this protein is as a hydrolase-oxidase enzyme. Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site.,Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, Camerini-Otero RD, Gilliland GL BMC Struct Biol. 2003 Sep 30;3:7. PMID:14519207 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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