1nyh
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Crystal Structure of the Coiled-coil Dimerization Motif of Sir4
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Structural highlights
FunctionSIR4_YEAST The proteins SIR1 through SIR4 are required for transcriptional repression of the silent mating type loci, HML and HMR. The proteins SIR2 through SIR4 repress mulitple loci by modulating chromatin structure. Involves the compaction of chromatin fiber into a more condensed form.[1] References
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This page was last modified 08:00, 14 February 2024.