1v5s
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Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
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Structural highlights
FunctionMARK3_MOUSE Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (By similarity). Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also | ||||||||||||||||||
This page was last modified 23:58, 27 December 2023.