1x41
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Solution structure of the Myb-like DNA binding domain of human Transcriptional adaptor 2-like, isoform B
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Structural highlights
FunctionTAD2A_HUMAN Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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This page was last modified 13:57, 9 May 2024.