1x5m
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Solution structure of the core domain of calcyclin binding protein; siah-interacting protein (SIP)
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Structural highlights
FunctionCYBP_HUMAN May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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This page was last modified 14:00, 9 May 2024.