1xhc

NADH oxidase /nitrite reductase from Pyrococcus furiosus Pfu-1140779-001

spinqualitylabelsall models 1xhc, resolution 2.35Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1xhc is a 1 chain structure with sequence from Pyrococcus furiosus DSM 3638. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.35Å Ligands: FAD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function NROR_PYRFU Catalyzes the NADH-dependent reduction of rubredoxin (Rd), a small iron-containing redox protein (PubMed:10464233, PubMed:11398485, PubMed:15746356). Can also reduce other electron carriers, including 2,6-dichlorophenol indophenol, benzyl viologen and menadione, but rubredoxin is the most efficient electron acceptor (PubMed:10464233, PubMed:11398485, PubMed:15746356). Does not reduce ferredoxin (PubMed:10464233). Shows comparable activity with NADPH and NADH as electron donors, but NADPH is probably the preferred physiological electron donor (PubMed:10464233, PubMed:11398485). Is probably part of an oxygen detoxification system that protects P.furiosus during exposure to oxygen (PubMed:15746356). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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