22rh

Phosphoglycerate mutase 1 complexed with a novel scaffold inhibitor

spinqualitylabelsall models 22rh, resolution 2.28Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 22rh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.28Å Ligands: A1E4P, CL, GOL, MES Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PGAM1_HUMAN Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.

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