29lk
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High-resolution structure of human SHMT2 in complex with PLP-Ser (external aldimine)
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Structural highlights
FunctionGLYM_HUMAN Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.[1] References
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This page was last modified 04:53, 13 August 2026.