2a26
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Crystal structure of the N-terminal, dimerization domain of Siah Interacting Protein
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Structural highlights
FunctionCYBP_HUMAN May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).[1] References
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This page was last modified 09:10, 14 February 2024.