2b6b

Cryo EM structure of Dengue complexed with CRD of DC-SIGN

Loading... Status: waiting for Mol* initialization Structural highlights 2b6b is a 4 chain structure with sequence from Dengue virus and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 25Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q9WDA7_9FLAV Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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