2e5z
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Solution structure of the surp2 domain in splicing factor, arginine/serine-rich 8
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Structural highlights
FunctionSFSWA_HUMAN Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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This page was last modified 18:47, 29 May 2024.