2f5u
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Structural Characterization of the UL25 DNA Packaging Protein from Herpes Simplex Virus Type 1
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Structural highlights
FunctionCVC2_HHV11 Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP. May mediate the capsid docking to the nuclear pore allowing entry of the viral genome into the host nucleus through binding to host nucleoporins NUP214.[HAMAP-Rule:MF_04025][1] [2] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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This page was last modified 09:21, 14 February 2024.