2gza

Crystal structure of the VirB11 ATPase from the Brucella Suis type IV secretion system in complex with sulphate

spinqualitylabelsall models 2gza, resolution 2.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2gza is a 3 chain structure with sequence from Brucella suis 1330. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.6Å Ligands: SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function VIRBB_BRUSU The VirB system could be required for the establishment of the replication niche in the host. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed VirB11 ATPases are hexameric assemblies that power type IV secretion systems in bacteria. The hexamer of Brucella suis VirB11 (BsB11), like that of the Helicobacter pylori VirB11 (Hp0525), consists of a double ring structure formed by the N-terminal and C-terminal domains of each monomer. However, the monomer differs dramatically from that of Hp0525 by a large domain swap that leaves the hexameric assembly intact but profoundly alters the nucleotide-binding site and the interface between subunits. A large domain swap in the VirB11 ATPase of Brucella suis leaves the hexameric assembly intact.,Hare S, Bayliss R, Baron C, Waksman G J Mol Biol. 2006 Jun 30;360(1):56-66. Epub 2006 May 11. PMID:16730027 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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