2jvg
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Structure of C3-binding domain 4 of Staphylococcus aureus protein Sbi
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Structural highlights
FunctionSBI_STAAM Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH. By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.[UniProtKB:A6QJQ7][1] References
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This page was last modified 06:42, 1 May 2024.