2kyl
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Solution structure of MAST2-PDZ complexed with the C-terminus of PTEN
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Structural highlights
FunctionMAST2_HUMAN Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).[UniProtKB:Q60592] See AlsoContents | ||||||||||||||||||
This page was last modified 05:37, 15 May 2024.