2l3f
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Solution NMR Structure of a putative Uracil DNA glycosylase from Methanosarcina acetivorans, Northeast Structural Genomics Consortium Target MvR76
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Structural highlights
FunctionHDG_METAC Excises hypoxanthine, a deamination product of adenine, from double-stranded DNA. Acts on double-stranded DNA containing G/I, T/I, A/I and C/I base pairs, but not on single-stranded inosine-containing DNA. Has also minor xanthine DNA glycosylase activity. Lacks any detectable uracil-DNA glycosylase activity.[1] References
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This page was last modified 06:52, 1 May 2024.