2pji

Solution structure of rhodostomin P48A mutant

spinqualitylabelsall models 2pji, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2pji is a 1 chain structure with sequence from Agkistrodon rhodostoma. This structure supersedes the now removed PDB entry 1xaz. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: RHOD (Agkistrodon rhodostoma) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Disintegrin

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