2vn8

Crystal structure of human Reticulon 4 interacting protein 1 in complex with NADPH

spinqualitylabelsall models 2vn8, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2vn8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.1Å Ligands: CIT, GOL, NA, NDP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease RT4I1_HUMAN Autosomal recessive isolated optic atrophy. The disease is caused by variants affecting the gene represented in this entry. Function RT4I1_HUMAN Plays a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury.[UniProtKB:Q924D0] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Proteopedia Page Contributors and Editors (what is this?)

OCA