2y3y

Holo-Ni(II) HpNikR is a symmetric tetramer containing four canonic square-planar Ni(II) ions at physiological pH

spinqualitylabelsall models 2y3y, resolution 2.39Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2y3y is a 5 chain structure with sequence from Helicobacter pylori G27 and Unidentified. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.39Å Ligands: EPE, NI, PEG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function NIKR_HELPG Transcriptional regulator.[HAMAP-Rule:MF_00476] Publication Abstract from PubMed The crystal structure of Helicobacter pylori holo-NikR, a Ni(2+)-dependent transcription factor, determined at pH 7.3, shows four square-planar nickel-binding sites, involving one cysteinate and three histidine ligands. This observation reconciles previous inconsistencies among calorimetric data, structural information at non-physiological pH, and computational studies. Holo-Ni(2+)Helicobacter pylori NikR contains four square-planar nickel-binding sites at physiological pH.,Benini S, Cianci M, Ciurli S Dalton Trans. 2011 Aug 21;40(31):7831-3. Epub 2011 Jul 4. PMID:21725560 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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