Structural highlights
31ew is a 2 chain structure with sequence from Aspergillus nidulans FGSC A4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | Electron Microscopy, Resolution 2.06Å |
| Ligands: | DAO, DGA, ERG, LMT, MYR, PLM |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
UAPA_EMENI Uric acid-xanthine transporter.[1] [2] [3]
References
- ↑ Koukaki M, Vlanti A, Goudela S, Pantazopoulou A, Gioule H, Tournaviti S, Diallinas G. The nucleobase-ascorbate transporter (NAT) signature motif in UapA defines the function of the purine translocation pathway. J Mol Biol. 2005 Jul 15;350(3):499-513. PMID:15953615 doi:https://dx.doi.org/10.1016/j.jmb.2005.04.076
- ↑ Goudela S, Karatza P, Koukaki M, Frillingos S, Diallinas G. Comparative substrate recognition by bacterial and fungal purine transporters of the NAT/NCS2 family. Mol Membr Biol. 2005 May-Jun;22(3):263-75. PMID:16096268 doi:https://dx.doi.org/10.1080/09687860500093016
- ↑ Gournas C, Amillis S, Vlanti A, Diallinas G. Transport-dependent endocytosis and turnover of a uric acid-xanthine permease. Mol Microbiol. 2010 Jan;75(1):246-60. doi: 10.1111/j.1365-2958.2009.06997.x. Epub, 2009 Dec 11. PMID:20002879 doi:https://dx.doi.org/10.1111/j.1365-2958.2009.06997.x
