32fd | pdb_000032fd

Cryo-EM structure of cariprazine-bound D3 dopamine receptor with mini-Go (alternative conformation)

spinqualitylabelsall models 32fd, resolution 2.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 32fd is a 5 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.9Å Ligands: 7RU Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease DRD3_HUMAN Hereditary essential tremor. Disease susceptibility is associated with variations affecting the gene represented in this entry. Function DRD3_HUMAN Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.

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