32zb

Cryo-EM structure of native, mature HERV-K hexameric capsomer

spinqualitylabelsall models 32zb, resolution 3.24Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 32zb is a 6 chain structure with sequence from Human endogenous retrovirus K. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.24Å Ligands: IHP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GAK8_HUMAN The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Endogenous Gag proteins may have kept, lost or modified their original function during evolution.

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