3bfx

Crystal structure of human sulfotransferase SULT1C1 in complex with PAP

spinqualitylabelsall models 3bfx, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3bfx is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entries 2etg and 1zhe. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.8Å Ligands: A3P Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ST1C2_HUMAN Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Sulfotransferase 3D structures

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