3bs7 | pdb_00003bs7
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Crystal structure of the Sterile Alpha Motif (SAM) domain of Hyphen/Aveugle
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Structural highlights
FunctionAVE_DROME Required for normal photoreceptor differentiation between Ras and Raf for EGFR signaling in the eye and for mitogen-activated protein kinase phosphorylation. Probably acts together with Cnk to promote Raf activation, perhaps by recruiting an activating kinase. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. | ||||||||||||||||||
This page was last modified 09:30, 21 February 2024.