3dkn

Sec61 in the Canine ribosome-channel complex from the endoplasmic reticulum

Loading... Status: waiting for Mol* initialization Structural highlights 3dkn is a 6 chain structure with sequence from Canis lupus familiaris. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 8.7Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function SECY_METJA The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Preprotein translocase 3D structures

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