3eh2 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
SC24C_HUMAN Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.[1][2][3]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
↑Tani K, Oyama Y, Hatsuzawa K, Tagaya M. Hypothetical protein KIAA0079 is a mammalian homologue of yeast Sec24p. FEBS Lett. 1999 Mar 26;447(2-3):247-50. PMID:10214955
↑Tang BL, Kausalya J, Low DY, Lock ML, Hong W. A family of mammalian proteins homologous to yeast Sec24p. Biochem Biophys Res Commun. 1999 May 19;258(3):679-84. PMID:10329445 doi:https://dx.doi.org/10.1006/bbrc.1999.0574
↑Pagano A, Letourneur F, Garcia-Estefania D, Carpentier JL, Orci L, Paccaud JP. Sec24 proteins and sorting at the endoplasmic reticulum. J Biol Chem. 1999 Mar 19;274(12):7833-40. PMID:10075675
