3j68

Structural mechanism of the dynein powerstroke (pre-powerstroke state)

Loading... Status: waiting for Mol* initialization Structural highlights 3j68 is a 1 chain structure with sequence from Strongylocentrotus purpuratus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 30Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DYHC_YEAST Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required to maintain uniform nuclear distribution in hyphae. May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast. Probably required for normal progression of the cell cycle. See Also Dynein 3D structures

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