3jb9

Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution

Loading... Status: waiting for Mol* initialization Structural highlights 3jb9 is a 17 chain structure with sequence from Schizosaccharomyces pombe and Schizosaccharomyces pombe 972h-. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.6Å Ligands: ADP, GDP, MG, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function SPP42_SCHPO Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity). Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. See Also Helicase 3D structures Pre-mRNA splicing factors 3D structures Sm-like protein 3D structures

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