3jc1

Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer

Loading... Status: waiting for Mol* initialization Structural highlights 3jc1 is a 68 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 4Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function IST1_HUMAN Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. See Also Charged multivesicular body protein 3D structures Increased sodium tolerance protein

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