3kbx

Human macrophage inflammatory protein-1 alpha L3M_V63M

spinqualitylabelsall models 3kbx, resolution 2.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3kbx is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.652Å Ligands: ACT, K, MSE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CCL3_HUMAN Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

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