3ozf

Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with hypoxanthine

spinqualitylabelsall models 3ozf, resolution 1.94Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3ozf is a 4 chain structure with sequence from Plasmodium falciparum FCR-3/Gambia. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.944Å Ligands: HPA, MG, PO4, POP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function HGXR_PLAFG Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Works with guanine, hypoxanthine and xanthine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. See Also Phosphoribosyltransferase 3D structures

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