3pdv

Structure of the PDlim2 PDZ domain in complex with the C-terminal 6-peptide extension of NS1

spinqualitylabelsall models 3pdv, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3pdv is a 1 chain structure with sequence from Homo sapiens and Influenza A virus (A/chicken/Henan/12/2004(H5N1)). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.2Å Ligands: NA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PDLI2_HUMAN Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity. See Also PDZ and LIM domain protein

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