3q3j

Crystal structure of plexin A2 RBD in complex with Rnd1

spinqualitylabelsall models 3q3j, resolution 1.97Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3q3j is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.971Å Ligands: GNP, MG, UNX Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PLXA2_HUMAN Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity). See Also GTP-binding protein 3D structures Plexin 3D structures Rho GTPase 3D structures

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